CompChem-Database: details for selected entry

CHEMBL5188034_s0_t1 (2529976)

FormulaC23H21N2O9PS
MW532.46
InChIKeyJRNJTHPVVWBNAO-PECIQRARNA-N
Entry_Date2023-09-01
Net_Charge0
Number_Atoms57
Number_Heavy_Atoms36
Number_Rings4
Number_Bonds60
Rotat_Bonds10
Unbranched_Chain2
Chiral_Centers0
ONatoms11
HB_Donor5
HB_Acceptor7
OpenEye_HB_Donors6
OpenEye_HB_Acceptors3
Lipinski_HB_Donors5
Lipinski_HB_Acceptors11
Lipinski_Violations2
XLogP30
XLogP1.55
logP5.8081
PSA207.16
MR134.684
ABS0.17
Solubilityhighly
AggregatorPass
PM7_Heat_of_Formation_kcal_per_mol-308.6921
PM7_Total_Energy_ev-6491.09606
PM7_Electronic_Energy_ev-57692.6814
PM7_Dipole_Debye1.83946
PM7_Point_GroupC1
PM7_HOMO_Energy_ev-7.979
PM7_LUMO_Energy_ev-1.714
PM7_COSMO_Area_square_ang450.56
PM7_COSMO_Volue_cubic_ang572.98
PM7_Electron_Affinity_ev1.714
PM7_Ionization_Energy_ev7.979
PM7_Energy_Gap_ev6.265
PM7_Global_Hardness_ev3.1325
PM7_Global_Softness_ev0.3192338387869114
PM7_Chemical_Potential_ev-4.8465
PM7_Electronigativity_ev4.8465
PM7_Back_Donation_Energy_ev-0.783125
PM7_Electrophilicity_ev3.7491719473264165
OPENEYE_Name4-[(~{E})-[dimethoxyphosphoryl-(4,5,9,10-tetrahydroxy-2-anthryl)methylene]amino]benzenesulfonamide
SMILESc1cc2c(c(c1)O)c(c3c(c2O)cc(cc3O)C(=Nc4ccc(cc4)S(=O)(=O)N)P(=O)(OC)OC)O
Canonical_SMILESCOP(=O)(/C(=N/c1ccc(cc1)S(=O)(=O)N)/c1cc(O)c2c(c1)c(O)c1c(c2O)c(O)ccc1)OC
InChI1/C23H21N2O9PS/c1-33-35(30,34-2)23(25-13-6-8-14(9-7-13)36(24,31)32)12-10-16-20(18(27)11-12)22(29)19-15(21(16)28)4-3-5-17(19)26/h3-11,26-29H,1-2H3,(H2,24,31,32)/f/h24H2
InChI_3D1S/C23H21N2O9PS/c1-33-35(30,34-2)23(25-13-6-8-14(9-7-13)36(24,31)32)12-10-16-20(18(27)11-12)22(29)19-15(21(16)28)4-3-5-17(19)26/h3-11,26-29H,1-2H3,(H2,24,31,32)/b25-23+
AuxInfo1/1/N:21,22,1,2,5,3,4,6,7,8,9,14,15,18,10,11,16,17,12,13,19,20,23,24,25,31,32,26,27,28,29,30,33,34,35,36/E:(1,2)(6,7)(8,9)(31,32)(33,34)/F:m/E:m/CRV:36.6/rA:57nCCCCCCCCCCCCCCCCCCCCCCCNNOOOOOOOOOPSHHHHHHHHHHHHHHHHHHHHH/rB:d1;;;s1;d3;s4;;;s2;d8;s10;s11;s8d9;s3d4;d5s12;s9d13;s6d7;d10s11;d12s13;;;s14;;s15w23;s19;s20;;;;s16;s17;s21;s22;s23d28s33s34;s18s24d29d30;s1;s2;s3;s4;s5;s6;s7;s8;s9;s21;s21;s21;s22;s22;s22;s24;s24;s26;s27;s31;s32;/rC:0,1.0056,0;.8679,1.5134,0;7.8135,-1.2408,0;6.0785,-1.2397,0;;7.8129,-2.246,0;6.0779,-2.2449,0;4.3415,1.5149,0;5.2158,.0003,0;1.7358,1.0056,0;3.4735,1.0078,0;1.7371,0,0;3.4738,-.0003,0;5.2154,1.0084,0;6.9463,-.7427,0;.8679,-.4978,0;4.3422,-.5013,0;6.945,-2.7531,0;2.6012,1.5123,0;2.6038,-.4989,0;8.0824,2.5066,0;6.0837,4.5078,0;6.0817,1.5078,0;6.9438,-4.7531,0;6.9475,1.0073,0;2.5985,2.5123,0;2.6028,-1.4989,0;5.0824,2.5085,0;7.9444,-3.7537,0;5.9444,-3.7525,0;.8676,-1.4978,0;4.3412,-1.5013,0;7.0824,2.5072,0;6.083,3.5078,0;6.0824,2.5078,0;6.9444,-3.7531,0;-.4337,1.2543,0;.8679,2.0134,0;8.2463,-.9904,0;5.646,-.9887,0;-.4327,-.2506,0;8.2465,-2.495,0;5.644,-2.4933,0;4.3406,2.0149,0;5.6486,-.2501,0;8.0821,2.0066,0;8.0827,3.0066,0;8.5824,2.5062,0;5.5837,4.5082,0;6.5837,4.5075,0;6.084,5.0078,0;7.3766,-5.0034,0;6.5106,-5.0028,0;2.1648,2.7611,0;3.0356,-1.7493,0;1.3005,-1.7479,0;4.7739,-1.7517,0;
DuplicatesCHEMBL5188034_s0_t1
mol2_Path/CCDB/ChEMBL/Database/Compound-0005150000-0005199999/Compound-0005188000-0005188249/CHEMBL5188034_s0_t1.mol2
pdbqt_Path/CCDB/ChEMBL/Database/Compound-0005150000-0005199999/Compound-0005188000-0005188249/CHEMBL5188034_s0_t1.pdbqt
sdf_Path/CCDB/ChEMBL/Database/Compound-0005150000-0005199999/Compound-0005188000-0005188249/CHEMBL5188034_s0_t1.sdf