CompChem-Database: details for selected entry

CHEMBL106449_p0_t1 (6796)

FormulaC12H26N11O6
MW420.41
InChIKeyHYZJMRBSIFBFFJ-IDGIRFDCNA-O
Entry_Date2023-09-01
Net_Charge1
Number_Atoms55
Number_Heavy_Atoms29
Number_Rings0
Number_Bonds54
Rotat_Bonds14
Unbranched_Chain4
Chiral_Centers2
ONatoms17
HB_Donor7
HB_Acceptor6
OpenEye_HB_Donors12
OpenEye_HB_Acceptors8
Lipinski_HB_Donors7
Lipinski_HB_Acceptors17
Lipinski_Violations2
XLogP30
XLogP-2.99
logP-0.3606
PSA292.29
MR104.27
ABS0.17
Solubilityhighly
AggregatorPass
PM7_Heat_of_Formation_kcal_per_mol94.72122
PM7_Total_Energy_ev-5632.33347
PM7_Electronic_Energy_ev-45407.81359
PM7_Dipole_Debye13.96662
PM7_Point_GroupC1
PM7_HOMO_Energy_ev-11.515
PM7_LUMO_Energy_ev-3.622
PM7_COSMO_Area_square_ang412.56
PM7_COSMO_Volue_cubic_ang473.72
PM7_Electron_Affinity_ev3.622
PM7_Ionization_Energy_ev11.515
PM7_Energy_Gap_ev7.893
PM7_Global_Hardness_ev3.9465
PM7_Global_Softness_ev0.25338907893069806
PM7_Chemical_Potential_ev-7.5685
PM7_Electronigativity_ev7.5685
PM7_Back_Donation_Energy_ev-0.986625
PM7_Electrophilicity_ev7.257340966679336
OPENEYE_Name[(1~{S})-4-[(~{Z})-[amino(nitramido)methylene]amino]-1-[[(1~{S})-4-[(~{Z})-[amino(nitramido)methylene]amino]-1-carbamoyl-butyl]carbamoyl]butyl]ammonium
SMILESC(=O)(C(CCCN=C(N)NN(=O)=O)NC(=O)C(CCCN=C(N)NN(=O)=O)[NH3+])N
Canonical_SMILESO=N(=O)N/C(=NCCC[C@@H](C(=O)N[C@H](C(=O)N)CCC/N=C(NN(=O)=O)/N)[NH3+])/N
InChI1/C12H25N11O6/c13-7(3-1-5-17-11(15)20-22(26)27)10(25)19-8(9(14)24)4-2-6-18-12(16)21-23(28)29/h7-8H,1-6,13H2,(H2,14,24)(H,19,25)(H3,15,17,20)(H3,16,18,21)/p+1/fC12H26N11O6/h13,19-21H,14-16H2/q+1
InChI_3D1S/C12H25N11O6/c13-7(3-1-5-17-11(15)20-22(26)27)10(25)19-8(9(14)24)4-2-6-18-12(16)21-23(28)29/h7-8H,1-6,13H2,(H2,14,24)(H,19,25)(H3,15,17,20)(H3,16,18,21)/p+1/t7-,8-/m0/s1
AuxInfo1/1/N:6,5,8,7,10,9,12,11,1,2,4,3,23,15,17,16,14,13,18,20,19,22,21,24,25,28,29,26,27/E:(26,27)(28,29)/F:m/E:m/CRV:22.5,23.5/rA:55cCCCCCCCCCCCCNNNNNNNNNNN+OOOOOOHHHHHHHHHHHHHHHHHHHHHHHHHH/rB:;;;;;s5;s6;s5;s6;s1s7;s2s8;w3s9;w4s10;s1;s3;s4;s2s11;s3;s4;s19;s20;s12;d1;d2;d21;d21;d22;d22;s5;s5;s6;s6;s7;s7;s8;s8;s9;s9;s10;s10;s11;s12;s15;s15;s16;s16;s17;s17;s18;s19;s20;s23;s23;s23;/rC:;-2.2321,-.866,0;2.9641,-3.866,0;-6.0981,-3.8301,0;1.2321,-1.866,0;-4.0981,-2.0981,0;.366,-1.366,0;-3.5981,-1.2321,0;2.0981,-2.366,0;-4.5981,-2.9641,0;-.5,-.866,0;-3.0981,-.366,0;2.9641,-2.866,0;-5.0981,-3.8301,0;-.5,.866,0;2.0981,-4.366,0;-6.5981,-2.9641,0;-1.366,-.366,0;3.8301,-4.366,0;-6.5981,-4.6962,0;4.6962,-3.866,0;-6.0981,-5.5622,0;-2.5981,.5,0;1,0,0;-2.2321,-1.866,0;5.5622,-4.366,0;4.6962,-2.866,0;-6.5981,-6.4282,0;-5.0981,-5.5622,0;1.4821,-1.433,0;.9821,-2.299,0;-3.6651,-2.3481,0;-4.5311,-1.8481,0;.116,-1.799,0;.616,-.933,0;-4.0311,-.9821,0;-3.1651,-1.4821,0;2.3481,-1.933,0;1.8481,-2.799,0;-4.1651,-3.2141,0;-5.0311,-2.7141,0;-.75,-1.299,0;-3.5311,-.116,0;-.25,1.299,0;-1,.866,0;1.6651,-4.116,0;2.0981,-4.866,0;-6.3481,-2.5311,0;-7.0981,-2.9641,0;-1.366,.134,0;3.8301,-4.866,0;-7.0981,-4.6962,0;-3.0311,.75,0;-2.3481,.933,0;-2.1651,.25,0;
DuplicatesCHEMBL106449_p0_t1;CHEMBL106449_p7_t0;CHEMBL106449_p7_t1;CHEMBL1202117_m2_p0_t1;CHEMBL1202117_m2_p7_t0;CHEMBL1202117_m2_p7_t1
mol2_Path/CCDB/ChEMBL/Database/Compound-0000100000-0000149999/Compound-0000106250-0000106499/CHEMBL106449_p0_t1.mol2
pdbqt_Path/CCDB/ChEMBL/Database/Compound-0000100000-0000149999/Compound-0000106250-0000106499/CHEMBL106449_p0_t1.pdbqt
sdf_Path/CCDB/ChEMBL/Database/Compound-0000100000-0000149999/Compound-0000106250-0000106499/CHEMBL106449_p0_t1.sdf