CompChem-Database: details for selected entry

CHEMBL108792 (9423)

FormulaC26H31N3O2
MW417.55
InChIKeyGCSFGDNMVLZHJL-VEORKLDJNA-N
Entry_Date2023-09-01
Net_Charge0
Number_Atoms62
Number_Heavy_Atoms31
Number_Rings3
Number_Bonds64
Rotat_Bonds10
Unbranched_Chain3
Chiral_Centers0
ONatoms5
HB_Donor2
HB_Acceptor2
OpenEye_HB_Donors2
OpenEye_HB_Acceptors2
Lipinski_HB_Donors2
Lipinski_HB_Acceptors5
Lipinski_Violations0
XLogP30
XLogP2.81
logP4.1633
PSA61.44
MR127.878
ABS0.55
Solubilitypoorly
AggregatorPass
PM7_Heat_of_Formation_kcal_per_mol-32.19393
PM7_Total_Energy_ev-4761.2651
PM7_Electronic_Energy_ev-43701.67252
PM7_Dipole_Debye6.54571
PM7_Point_GroupC1
PM7_HOMO_Energy_ev-8.123
PM7_LUMO_Energy_ev0.096
PM7_COSMO_Area_square_ang440.89
PM7_COSMO_Volue_cubic_ang550.16
PM7_Electron_Affinity_ev-0.096
PM7_Ionization_Energy_ev8.123
PM7_Energy_Gap_ev8.219
PM7_Global_Hardness_ev4.1095
PM7_Global_Softness_ev0.24333860566978952
PM7_Chemical_Potential_ev-4.0135
PM7_Electronigativity_ev4.0135
PM7_Back_Donation_Energy_ev-1.027375
PM7_Electrophilicity_ev1.9598713042949263
OPENEYE_Name1,4,4-trimethyl-~{N}3,~{N}5-bis(2-phenylethyl)pyridine-3,5-dicarboxamide
SMILESc1ccc(cc1)CCNC(=O)C2=CN(C=C(C2(C)C)C(=O)NCCc3ccccc3)C
Canonical_SMILESCN1C=C(C(=O)NCCc2ccccc2)C(C(=C1)C(=O)NCCc1ccccc1)(C)C
InChI1/C26H31N3O2/c1-26(2)22(24(30)27-16-14-20-10-6-4-7-11-20)18-29(3)19-23(26)25(31)28-17-15-21-12-8-5-9-13-21/h4-13,18-19H,14-17H2,1-3H3,(H,27,30)(H,28,31)/f/h27-28H
InChI_3D1S/C26H31N3O2/c1-26(2)22(24(30)27-16-14-20-10-6-4-7-11-20)18-29(3)19-23(26)25(31)28-17-15-21-12-8-5-9-13-21/h4-13,18-19H,14-17H2,1-3H3,(H,27,30)(H,28,31)
AuxInfo1/1/N:20,21,22,1,2,3,4,5,6,7,8,9,10,23,24,25,26,13,14,11,12,15,16,17,18,19,28,29,27,30,31/E:(1,2)(4,5)(6,7,8,9)(10,11,12,13)(14,15)(16,17)(18,19)(20,21)(22,23)(24,25)(27,28)(30,31)/gE:(1,2)/F:m/E:m/rA:62nCCCCCCCCCCCCCCCCCCCCCCCCCCNNNOOHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH/rB:;d1;s1;d2;s2;s3;d4;s5;d6;d7s8;d9s10;;;d13;d14;s15;s16;s15s16;s19;s19;;s11;s12;s23;s24;s13s14s22;s17s25;s18s26;d17;d18;s1;s2;s3;s4;s5;s6;s7;s8;s9;s10;s13;s14;s20;s20;s20;s21;s21;s21;s22;s22;s22;s23;s23;s24;s24;s25;s25;s26;s26;s28;s29;/rC:-7.584,-2.3925,0;7.584,-2.3924,0;-6.7187,-2.8937,0;-7.5884,-1.3924,0;6.7187,-2.8937,0;7.5884,-1.3924,0;-5.8489,-2.3899,0;-6.7186,-.8886,0;5.8489,-2.3899,0;6.7186,-.8886,0;-5.8444,-1.3847,0;5.8444,-1.3847,0;-.8675,1.5027,0;.8675,1.5027,0;-.8675,.4975,0;.8675,.4975,0;-2.3818,-.3797,0;2.3818,-.3797,0;;.642,-.7667,0;-1.1236,-1.3417,0;0,3.0104,0;-4.9791,-.8835,0;4.9791,-.8835,0;-4.1138,-.3822,0;4.1138,-.3822,0;0,2.0104,0;-3.2485,.119,0;3.2485,.119,0;-2.3803,-1.3797,0;2.3803,-1.3797,0;-8.0167,-2.6431,0;8.0167,-2.6431,0;-6.7187,-3.3937,0;-8.0221,-1.1437,0;6.7187,-3.3937,0;8.0221,-1.1437,0;-5.4163,-2.6405,0;-6.7208,-.3886,0;5.4163,-2.6405,0;6.7208,-.3886,0;-1.3012,1.7514,0;1.3012,1.7514,0;.2587,-1.0877,0;.9631,-1.15,0;1.0254,-.4456,0;-.7402,-1.6627,0;-1.5069,-1.0206,0;-1.4446,-1.725,0;-.5,3.0104,0;.5,3.0104,0;0,3.5104,0;-4.7285,-1.3161,0;-5.2297,-.4508,0;4.7285,-1.3161,0;5.2298,-.4508,0;-3.8632,-.8149,0;-4.3645,.0504,0;3.8632,-.8149,0;4.3645,.0504,0;-3.2492,.619,0;3.2492,.619,0;
DuplicatesCHEMBL108792
mol2_Path/CCDB/ChEMBL/Database/Compound-0000100000-0000149999/Compound-0000108750-0000108999/CHEMBL108792.mol2
pdbqt_Path/CCDB/ChEMBL/Database/Compound-0000100000-0000149999/Compound-0000108750-0000108999/CHEMBL108792.pdbqt
sdf_Path/CCDB/ChEMBL/Database/Compound-0000100000-0000149999/Compound-0000108750-0000108999/CHEMBL108792.sdf